ProbioFit: Supporting Fitness Naturally

From Traditional Kimchi Fermentation to Cutting-Edge Fitness

ProbioFit (TCI378), a powerful probiotic strain isolated from Korean kimchi, is capturing attention for its clinically proven fat-reducing benefits. Developed by TCI through its advanced Bioresource Data Mining platform, this innovative strain is changing how we think about probiotics and weight management.

Unlike traditional probiotics that focus mainly on digestion, ProbioFit is designed to help manage weight and reduce fat absorption naturally. Its mode of action is both innovative and effective. It produces bile salt hydrolase (BSH), an enzyme that breaks down bile salts in the gut, disrupting the process that allows fats to emulsify and be absorbed. This means less dietary fat is stored, and more is excreted from the body, a simple, natural way to support a healthier metabolism.

Clinically Proven to Trim Fat and Slim Waistlines

In a 14-day human trial, adults who supplemented with ProbioFit experienced^*:

• 0.9 kg weight loss
• 0.3 drop in BMI
• 2.0% reduction in total body fat
• 2.9% reduction in trunk fat
• 1.6 cm slimmer waistline
• 73% reported improved bowel movements

These impressive results were achieved without medication or dietary restrictions with just servings per day.

Learn more about TCI probiotics

A Healthier, Happier Body Starts in the Gut

TCI378 supports metabolism with a triple-action mechanism:

1. Blocks Fat Absorption: Thanks to its high bile salt hydrolase (BSH) activity, TCI378 breaks down bile salts, disrupting fat emulsification and reducing cholesterol formation by 47.6%.^[1]
2. Reduces Fat Storage: The strain suppresses GLUT4 (glucose uptake gene) by 54% and PLIN1 (adipocyte protection gene) by 48%, encouraging fat breakdown.^[2,3]
3. Fights Fat Accumulation: In lab studies, ProbioFit reduced fat droplet accumulation in fat cells by 15%, thanks to three potent bioactive compounds naturally produced by the strain.

As demand continues to grow for science-backed supplements that align with real-world eating habits, ProbioFit stands out as a powerful tool for those who want to enjoy their meals and still meet their health goals. This is not just another probiotic. It’s a smarter way to approach fat management, backed by science and inspired by tradition.

*Data from TCI Internal Study

[1] Huang, C. H., Ho, C. Y., Chen, C. T., Hsu, H. F., & Lin, Y. H. (2019). Probiotic BSH activity and anti-obesity potential of Lactobacillus plantarum strain TCI378 isolated from Korean Kimchi. Preventive nutrition and food science, 24(4), 434.

[2] Friedman, J. E., Dohm, G. L., Leggett-Frazier, N., Elton, C. W., Tapscott, E. B., Pories, W. P., & Caro, J. F. (1992). Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. The Journal of clinical investigation, 89(2), 701-705.

[3] Grahn, T. H. M., Zhang, Y., Lee, M. J., Sommer, A. G., Mostoslavsky, G., Fried, S. K., … & Puri, V. (2013). FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes. Biochemical and biophysical research communications, 432(2), 296-301.